interleukin12

介白質十二(Interleukin-12, IL-12) 是異二聚體(heterodimer) 細胞激素，由p35和p40亞基(subunit) 組成，主要會促進第1型輔助性T細胞（T helper 1 cells, TH1）的分化 ...

由 KAM Ullrich 著作 · 2020 · 被引用 54 次 — Taken together, IL-12 is a potent cytokine to regulate the immune response in different ways. Thus, its implication in immune-mediated diseases is obvious and ...

Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, helper T cells and human B-lymphoblastoid ...

Interleukin 12 (IL-12) is a cytokine that is produced by myeloid and other cell types. It induces TH1 differentiation in T-lymphocytes and the subsequent ...

Interleukin-12 (IL-12), p80 · 30R-AI108 · Brand · Description · Application · Reactivity · Photos · 歡迎填寫資料獲得亞旭第一手資訊.

由 G Trinchieri 著作 · 2003 · 被引用 4681 次 — Interleukin-12 (IL-12) is a heterodimeric pro-inflammatory cytokine that regulates T-cell and natural killer-cell responses, induces the ...

由 J Liu 著作 · 2005 · 被引用 143 次 — Interleukin-12 (IL-12) is a heterodimeric cytokine composed of the p35 and p40 subunits. It is produced by antigen-presenting cells and plays a critical ...

由 KG Nguyen 著作 · 2020 · 被引用 248 次 — Interleukin-12 (IL-12) is a potent, pro-inflammatory type 1 cytokine that has long been studied as a potential immunotherapy for cancer.

2019年6月4日 — IL-12 是由p35 和p40 兩個subunit 所組成約70~75kDa 的二聚體醣蛋白質，很多細胞都能生成p35，但是只有被活化的monocyte/marcophage 才能生成p40。

2020年4月17日 — 研究團隊認為修飾後的CBD–IL-12 改變原本IL-12 的特性，將有望突破現有免疫治療的瓶頸，擴大免疫治療在多種癌症上的臨床應用效果。